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Thonzonium Bromide
CAS No. 553-08-2
Thonzonium Bromide( —— )
Catalog No. M15007 CAS No. 553-08-2
Thonzonium bromide is a monocationic detergent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
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| 10MG | 42 | In Stock |
|
| 25MG | 85 | In Stock |
|
| 50MG | 160 | In Stock |
|
| 100MG | 241 | In Stock |
|
| 500MG | 597 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThonzonium Bromide
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NoteResearch use only, not for human use.
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Brief DescriptionThonzonium bromide is a monocationic detergent.
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DescriptionThonzonium bromide is a monocationic detergent.(In Vitro):Thonzonium bromide inhibits RANKL-induced OC formation, the appearance of OC-specific marker genes and bone-resorbing activity in vitro. Thonzonium bromide blocks the RANKL-induced activation of NF-κB, ERK and c-Fos as well as the induction of NFATc1 which is essential for OC formation. Thonzonium bromide disrupts F-actin ring formation resulting in disturbances in cytoskeletal structure in mature OCs during bone resorption. Thonzonium bromide exhibits protective effects in an in vivo murine model of LPS-induced calvarial osteolysis.
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In VitroThonzonium bromide inhibits RANKL-induced OC formation, the appearance of OC-specific marker genes and bone-resorbing activity in vitro. Thonzonium bromide blocks the RANKL-induced activation of NF-κB, ERK and c-Fos as well as the induction of NFATc1 which is essential for OC formation. Thonzonium bromide disrupts F-actin ring formation resulting in disturbances in cytoskeletal structure in mature OCs during bone resorption. Thonzonium bromide exhibits protective effects in an in vivo murine model of LPS-induced calvarial osteolysis.
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorDHPS
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number553-08-2
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Formula Weight591.71
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Molecular FormulaC32H55BrN4O
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Purity>98% (HPLC)
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SolubilityDMSO: > 10 mM
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SMILES[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)CCN(CC1=CC=C(OC)C=C1)C1=NC=CC=N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Neriifolin
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Pyronine B
Pyronine B (NSC 44690) is a fluorophore with low relative fluorophore brightness and a small hydrophobic (SH) protein channel inhibitor, which is used for staining of bacteria and mycobacteria and in the spectrophotometric determination of ultra-trace ruthenium.
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MPP+ iodide
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra.
